Abstract: According to the traditional positivist, science, presupposing universalism of science because of Knowledge sharing for all humanity, is independent of society and politics, which provides the theoretical foundation for international cooperation of science. Nowadays, however, this view of Science has been challenged in international cooperation. Analysing the event of NASA “China exclusion” on scientific research, we can find that American government adopted many intervention modes, such as legislation, finance, to control scientific cooperation, and under the pretext of “National Security”, containment and blockade rising country including China, which set up obstacles for international cooperation in science. Facing the Challenge, we should strengthen the consciousness of the politicization of science in globalization era, safeguard the national security by competition and struggle in scientific research cooperation, meanwhile，we also should strengthen independent innovation and strive for more discourse power in international cooperation， which can really break the blockade by western countries in science and technology.

摘要： 传统的实证主义科学观将科学独立于政治之外，并预设了科学知识全人类共享的科学普遍主义，这为科学的国际合作提供了理论基础。但这种科学观在当今国际科研合作中却受到了挑战。分析NASA科研“排华”事件可发现，美国政府采取了立法、财务等多种模式对科研合作进行管控与干预，以“国家安全”为名对以中国为代表的崛起国进行遏制与封锁，为科技合作设置重重障碍。面对挑战，我们应增强对全球化时代科学政治化的自觉性，在参与科研合作时既合作又竞争，更要切实维护国家安全，在自主创新中增强国际合作中的科学话语权，真正打破西方国家在科技上对中国的限制和封锁。