Abstract: Gene editing technology, as the most representative subversive technology in contemporary times, brings huge opportunities for human development while also posing many challenges by modifying life genes. This technology has broken through the traditional definition of life and the once unquestionable realm of life, directly touching on the existing ethical positioning of the intrinsic value of life and triggering a crisis of human dignity. At the three levels of nature, individuals, and society, this crisis of human dignity is manifested as a crisis of life dignity, a crisis of personal dignity, and a crisis of human dignity. To ensure the safety and proper use of this technology, relevant laws and ethical guidelines need to be formulated. Gene editing technology should be based on the principles of "people-oriented, scientific rigor, fairness and openness, early warning and accountability", balance the tension between the development of genetic technology and the value system of life ethics, construct a "soft landing" mechanism for the development of gene editing technology, establish a new ethical cognitive schema and new forms of ethical norms, so as to better safeguard human dignity and promote human development.

摘要： 基因编辑技术作为当代最具代表性的颠覆性技术，通过改造生命基因，在给人类发展带来巨大机遇的同时，也造成诸多挑战。基因编辑技术突破了对生命的传统定义以及曾经不可置疑的生命范畴，直接触动了关于生命内在价值的已有伦理定位，引发人的尊严危机。在自然、个体和社会三个层面，人的尊严危机表现为生命尊严危机、人格尊严危机和人性尊严的危机。为确保技术安全及合理使用，需要制定相关的法律和伦理准则。基因编辑技术应基于“以人为本、科学谨严、公平公开、预警追责”的原则，平衡基因技术发展与生命伦理价值体系之间的张力,构建基因编辑技术发展的“软着陆”机制，确立新的伦理认知图式和伦理规范新样态，更好地维护人的尊严，促进人类发展。