Abstract: Industry-university-research institute（IUR）collaborative innovation has become the leading-edge innovation mode to promote significant knowledge and technological innovation in China. IUR collaborative innovation process can be regarded as the flow of knowledge between enterprises and universities（or research institutions）two types of heterogeneous knowledge organization.Therefore， this paper divided IUR collaborative innovation process into three progressive evolution stages from the perspective of knowledge-flow， including knowledge sharing， knowledge creation and formation of knowledge advantage， analyzed internal operation mechanism and synergistic characteristics of the whole process， initially established a theoretical framework of industry-university-research institute collaborative innovation process based on knowledge flow

摘要： 产学研协同创新目前已成为我国推动重大知识与技术创新的前沿创新模式，产学研协同创新过程可以视为企业和大学（或科研机构）两类异质性知识组织之间知识流动的过程。因此，本文基于知识流动的视角，将产学研协同创新过程分为知识共享、知识创造和知识优势的形成三个递进演化阶段，分析了各阶段运行的内在机理，并在此基础上探讨了产学研协同创新过程的协同特征，初步构建了基于知识流动的产学研协同创新过程的理论框架。

关键词: 知识流动, 产学研协同创新, 协同创新过程, Knowledge Flow, Industry-university-research institute（IUR）collaborative innovation , Process of collaborative innovation