Abstract: This study aims to systematically explore the multi-dimensional impact of China's regional Science and Technology Innovation Corridors (STIC) on economic growth, focus on the "dual characteristics". Based on the spatial dynamic panel model (SDM-DID), the panel data of 75 cities covering the three STICs (namely G60 STIC, Guangzhou-Shenzhen-Hong Kong-Macao STIC, and Beijing-Tianjin-Hebei STIC) and their surrounding cities from 2010 to 2021 were empirically tested. This study reveals the significant effect of STIC s in promoting the economic growth. However, the economic effect of the surrounding cities shows obvious inhibitions. This "dual characteristic" mainly stems from the asymmetry of agglomeration effect: in the corridor, the triple agglomeration effect of capital, talent and technology shows an obvious promotion effect. In contrast, in the surrounding cities, these agglomeration effects translate into the "siphon effect" of technology, resulting in the loss of capital and talent, which in turn inhibits their economic growth. In addition, as a regional growth pole, the STICs forms a "gathering shadow area" within a range of 350km around the corridor. When the shadow area exceeds a certain range, the radiation effect of the growth pole is obvious. It emphasizes that, in the construction of STICs, it is necessary to consider more carefully the possible negative impact on surrounding cities to achieve regional development sustainably. This study provides a new theoretical perspective for understanding the complexity and multi-dimensionality of STICs, also provides academic support and policy recommendations for government planning and decision-making.