Abstract: Chips are a place of contention for major powers in the fourth industrial revolution. Although the chip industry chain has become highly globalized, various international events in recent years have shown that the United States still has a hegemonic position in this field and has the ability to “weaponize” chips to sanction other countries. Why did the United States build a “Chip hegemony”, and how did this hegemony come about? This paper argues that “Chip hegemony” is an important weight for the United States to continue the “Center-periphery” dual dependency structure in the world system, which constitutes a strong motivation for the United States to frequently suppress the catching up countries in order to maintain its own control. Technology monopoly, financial domination, and market control together form the three pillars of the United States’ “Chip hegemony”, and it is the control of these three areas that makes the United States always control the key links in the global chip ecology. In the face of the increasing chip sanctions by the United States, China should also give full play to its political and economic system advantages to prescribe the right medicine, and gradually achieve strategic breakthroughs in these three areas and the contrarian rise of the entire chip industry.