Abstract: Organized interdisciplinary research in universities is a key form of organized scientific research, focusing mainly on the intersection of similar disciplines in natural and engineering disciplines. Under the perspective of expected governance, the promotion of organized cross-disciplinary research in universities has formed a progressive four-part process, which aims to foresee the diversified prospects of cross-disciplinary research in the light of collective interests, to advocate the integration of multiple subjects into the rationale and practical transformation chain of cross-disciplinary research, to integrate cross-disciplinary projects and educational activities in the face of the complex challenges of reality, and to build an open and holistic framework based on a unified vision, collective wisdom, and cultural infiltration. Looking to the future, universities should organize themselves to enhance their capacity and create a strategic foresight network for cross-disciplinary research; encourage diversified participation and build a cross-domain scientific and technological decision-making community; strengthen internal integration and promote cross-disciplinary projects and educational activities; cultivate a culture of openness, and carry forward the cross-disciplinary research governance experience with Chinese characteristics, so as to become an effective framework for the integration of education, science and technology, and human resources in China. It will also foster an open culture and promote the experience of cross-disciplinary research governance with Chinese characteristics, so as to make it an effective aid for the integration of education, science and technology, and talents in China.